Oct 29 2009

Manipulating Phantom Limbs

A phantom limb sensation sometimes persists after amputation – the real limb is gone, but the person feels as if the limb remains. They can feel it, and even “move” it. Phantom limbs are one of my favorite examples of the fact that our brains construct an internal model of reality (and our bodies are included in that model), and like all biological processes, that process can go awry. Deprived of sensory and motor feedback from the missing limb, sometimes those bits of the brain (the insular cortex) that give us a sense of ownership and agency over a limb continue to function, manifesting a phantom limb to own and manipulate.

In rare cases, this process can lead to the emergence of a supernumerary phantom limb – a third (or fourth or fifth) arm that the person can feel and manipulate.

Researchers Moseley and Brugger recently published a study involving seven subjects with phantom limbs post-amputation. Their question was whether or not the subjects could be made to move their phantom limbs in anatomically impossible ways. They did this by giving them tasks to imagine with their phantom limbs, tasks that would be quick to accomplish by bending their wrist back in a normally impossible way.

Four of the seven subjects reported successfully completing the task. This was experimentally confirmed by timing the subjects in completing their tasks – which were more quickly completed by using the impossible movements.

What is most interesting is that once the subjects successfully moved their phantom limbs in the new way, their internal image of their phantom limb morphed to accommodate the new movement – including a modified wrist joint over which they had a sense of ownership. This change was further corroborated by the fact that previously simple tasks were made more difficult by the new joint configuration.

In other words – the subjects’ internal model of their phantom limb changed as a result of conscious effort to use the limb in new ways. The subjective ease and difficulty of tasks then conformed to the new anatomical model of the phantom limb. What this likely means is that there is a high degree of plasticity in those brain regions that create our internal model of or body parts and ownership over those body parts. This is consistent with the more basic observation that phantom limbs, and especially supernumerary phantom limbs, can exist in the first place.

There are two apparent applications for this plasticity. The first is as a therapeutic option for those with phantom limbs. Sometimes, the phantom limbs are contorted or contracted in uncomfortable positions. Encouraging patients with painful phantom limbs to imagine a task that will relieve the painful position may be an effective treatment. Other interventions have also been used successfully – such as presenting subjects with a virtual image of their phantom limb, which moves into a more comfortable position, triggering their internal model to do so.

And this example brings up the second application for the apparent plasticity of our internal model of our own bodies – prosthetics and virtual reality. In a “six million dollar man” scenario, where an amputee is given a robotic limb, it is plausible that recipients may be made to feel ownership over their new limb, rather than feeling as if they have something attached to their body. Sensory and motor feedback is helpful – but this study suggests it is not even necessary – imagining may be sufficient.

Further, as the world of virtual reality looms before us, it is plausible that our brains can be easily tricked into feeling as if we occupy the virtual representation of ourselves. We will not just be looking at an our avatar in a virtual world, but feel as if we are the avatar and are in the virtual world.

It remains to be seen how easy this will be to accomplish, and how complete the sensation will be. It may be that some sense of ownership will be possible, but will feel unnatural and disconcerting. Or it may be that most people will require considerable training to functionally occupy their virtual selves. Perhaps only the next generation, who begin the process at a young age, will become truly comfortable in their virtual selves. It may also take some time to understand and tweak the process until it becomes practical and comfortable for most people.

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5 responses so far

5 Responses to “Manipulating Phantom Limbs”

  1. CharlesGon 29 Oct 2009 at 10:49 am

    Perhaps the most interesting, or at least novel, aspect of this to my mind is that this indicates the plasticity of these parts of the brain is great enough that people could have a sense of ownership over, and intuitive use of, prosthetic or virtual limbs that don’t resemble the human norm. Of course the virtues of prosthetics that aren’t built to emulate as closely as possible the limb(s) replaced are open to debate, but perhaps this will encourage a closer look at the potential.

  2. Eternally Learningon 29 Oct 2009 at 1:06 pm

    Steve,

    This has to be one of my favorite topics of yours. The concept that what we are experiencing every day is a construct of our brain to interact with reality is life-altering in ways that we probably haven’t even thought of yet. I don’t know if you caught the DVD release of Caprica’s series premiere, but there is a lot of what you are talking about represented in it.

    Please continue to talk about this stuff ad naseum : )

  3. omdixon 30 Oct 2009 at 2:04 am

    Steve,

    I always enjoy when you discuss neuroscience (and most everything else, too)! I had come across the topic of phantom limbs from a presentation given by V. S. Ramachandran in the videos Beyond Belief: Candles in the Dark (it also, recently, came up on House). However, I’m not sure, but the idea of relieving the pain of a contorted phantom limb by allowing the patient to reposition a virtual image, seems not to mesh with a statement made on SGU during science or fiction from podcast 46 – June 7, 2006. (I was recently relistening to some oldies-but-goodies.)

    The statement was that phantom limb pain seems to originate from the nerves in the limb, itself, rather than being psychosomatic. I’m not wanting to sound nit-picky; I’m sincerely misunderstanding this aspect. How is pain originating in the nerves of the limb alleviated by an alteration of the parts of the brain governing a model of our body parts? Does this part of the brain monitor pain in those limbs as well? Is there an alteration in other areas that do detect pain? Reinterpretation of the pain signal?

    My ignorance of neuroscience is probably apparent. Any illumination you can provide would be most appreciated.

  4. CodeSculptoron 30 Oct 2009 at 2:20 am

    I hope that one day we can exploit this, in the future, to manufacture more useful prosthetics with regard to the interface. Well, by that point, we’ll probably be able to effectively clone or grow an effective replacement.
    But that doesn’t mean I support the supernumerary limbs… I won’t accept my son dating an octopus, even if she has red-hair.

  5. petrossaon 09 Nov 2009 at 5:28 am

    I am a total layman, but i tried to put together a theory i had.
    This post added to my thesis that in actual fact we live in a virtual world already.
    I’ve made thread somewhere else, but that’s not on a professional blog.

    Would someone be so kind to shoot holes in it?
    http://www.neowin.net/forum/index.php?showtopic=841080

    PS
    go easy on me

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