Archive for the 'Science and Medicine' Category

Jul 25 2014

Mike Adams is a Dangerous Loon

Where do I even begin? Mike Adams, the self-proclaimed “healthranger” who runs the crank alt-med site naturalnews, has sunk to a new low, even though he was already scraping bottom.

Adams combines the worst CAM propaganda with a blend of conspiracy theories from across the spectrum, while selling supplements and other nonsense. He portrays himself as someone who is engaged in a righteous battle against the forces of evil – so hardly someone who is engaged in rational discourse.

In a recent rant, however, he has become a parody even of himself. This time he is raving about Monsanto and GMOs, writing:

Monsanto is widely recognize (sic) as the most hated and most evil corporation on the planet. Even so, several internet-based media websites are now marching to Monsanto’s orders, promoting GMOs and pursuing defamatory character assassination tactics against anyone who opposes GMOs, hoping to silence their important voices.

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Jul 23 2014

Another Lawsuit To Suppress Legitimate Criticism – This Time SBM

I suppose it was inevitable. In fact, I’m a bit surprised it took this long. SGU Productions, the Society for Science-based medicine, and I are being sued for an article that I wrote in May of 2013 on Science-Based Medicine. My SBM piece, which was inspired by an article in the LA Times, gave this summary:

“The story revolves around Dr. Edward Tobinick and his practice of perispinal etanercept (Enbrel) for a long and apparently growing list of conditions. Enbrel is an FDA-approved drug for the treatment of severe rheumatoid arthritis. It works by inhibiting tumor necrosis factor (TNF), which is a group of cytokines that are part of the immune system and cause cell death. Enbrel, therefore, can be a powerful anti-inflammatory drug. Tobinick is using Enbrel for many off-label indications, one of which is Alzheimer’s disease (the focus of the LA Times story).”

The claims and practice of Dr. Tobinick have many of the red flags of a dubious medical practice, of the sort that we discuss regularly on SBM. It seems that Dr. Tobinick does not appreciate public criticism of his claims and practice, and he wants me to remove the post from SBM. In my opinion he is using legal thuggery in an attempt to intimidate me and silence my free speech because he finds its content inconvenient.

Of course, we have no intention of removing the post as we feel it is critical to the public’s interest. This is what we do at SBM – provide an objective analysis of questionable or controversial medical claims so that consumers can make more informed decisions, and to advance the state of science in medicine.
We also feel it is critical not to cave to this type of intimidation. If we do, we might as well close up shop (which I suspect the Tobinicks of the world would find agreeable). Defending against even a frivolous lawsuit can be quite expensive, but we feel it is necessary for us to fight as hard as we can to defend our rights and the work that we do here at SBM.

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Jul 18 2014

New Organic Farming Meta-analysis – What Does it Really Show?

The Guardian’s headline reads: Clear differences between organic and non-organic food, study finds. While this article was better than most in including some caveats, it was clearly favorable to the conclusions in the study, and failed, in my opinion, to properly put the new study into an informative context.

How does this new study add to the literature looking at the safety and health effect of organic produce vs conventional produce?

First, the study is a meta-analysis of 343 prior studies looking at nutrient content, pesticide, and heavy metal contamination of produce. It is not a collection of any new data. A meta-analysis is very tricky to conduct well – it does not improve the quality of the data going into the analysis, only the statistical power. Further it introduces another layer of potential bias (another researcher degree of freedom) in which studies are chosen for the analysis.

This study used very open criteria, and therefore included more lower-quality studies (likely to be false positive or show the bias of the researchers) than other meta-analyses.

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Jul 15 2014

BBC Fail on Acupuncture Documentary

Alternative Medicine’s best friend, and in my opinion largely responsible for what popularity it has, is a gullible media. I had thought we were turning a corner, and the press were over the gushing maximally clueless approach to CAM, and were starting to at least ask some probing questions (like, you know, does it actually work), but a 2006 BBC documentary inspires a more pessimistic view.

The documentary is part of a BBC series hosted by Kathy Sykes: Alternative Medicine, The Evidence. This episode is on acupuncture. The episode is from 2006, but was just posted on YouTube as a “2014 documentary.” Unfortunately, old news frequently has a second life on social media.

First, let me point out that Sykes is a scientist (a fact she quickly points out). She is a physicist, which means that she has the credibility of being able to say she is a scientist but has absolutely no medical training. It’s the worst case scenario – she brings the credibility of being a scientist, and probably thinks that her background prepares her to make her own judgments about the evidence, and yet clearly should have relied more on real experts.

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Jul 03 2014

Vaccine Safety Systematic Review

A new systematic review of adverse events from vaccines used in the US was recently published in the journal Pediatrics: Safety of Vaccines Used for Routine Immunization of US Children: A Systematic Review. (Full text pdf) This systematic review is actually an update and expansion to the 2011 Institute of Medicine (IOM) report on vaccine side effects.

The review looked at the best evidence available, active surveillance studies with controls, identifying 67 relevant studies. Overall they found that vaccines were very safe. There were a few associations with serious adverse events, but these were all very rare. From their conclusions:

Our findings may allay some patient, caregiver, and health care provider concerns. Strength of evidence is high that MMR vaccine is not associated with the onset of autism in children; this conclusion supports findings of all previous reviews on the topic. There is also high-strength evidence that MMR, DTaP, Td, Hib, and hepatitis B vaccines are not associated with childhood leukemia.

Evidence was found for an association of several serious AEs with vaccines; however, these events were extremely rare: absolute risk is low. For example, strength of evidence is moderate for association of vaccines against rotavirus with intussusception. Although 1 large US epidemiologic study found no association, a recent analysis of the US PRISM program found both RotaTeq and Rotarix associated with intussusception in the short term. Estimated rates were 1.1 to 1.5 cases per 100 000 doses of RotaTeq and 5.1 cases per 100 000 doses of Rotarix.

So a few vaccines are associated with rare AEs. Given the rhetoric of the anti-vaccine movement, there are a few points worth emphasizing here.

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Jun 26 2014

Pesticides and Autism

A study has been making the rounds on social media claiming an association between prenatal exposure to pesticides and the risk of autism and developmental delay. This means that I am getting asked by many people what the study actually shows. Spoiler alert – not much. But let’s break it down.

Autism spectrum disorder (ASD) is a neurological disorder involving brain development resulting in decreased communications among neurons in the brain and characterized by reduced social ability. Our current scientific understanding is that ASD is largely a genetic disorder. While environmental factors cannot be ruled out, it seems that genes are the primary factor. It’s reasonable to search for environmental risk factors, but so far none have been clearly established.

Those who feel there likely is an environmental factor also tend to believe that there is an autism epidemic – that the incidence of autism is increasing in a way that is not easily explained by genetics, and therefore suggests and environmental factor. While it is uncontroversial that the number of ASD diagnoses has been increasing over the last two decades, this does not necessarily mean that the true incidence of ASD has been increasing.

The evidence actually shows that diagnostic substitution, broadening of the definition of ASD, and increased surveillance account for much of the increased recorded incidence. It’s possible that changes in diagnostic behavior entirely accounts for the apparent increase. It’s also possible that a subset is due to a true increase, but that has not been clearly established.

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Jun 06 2014

PETA Responds

Last week on Science-Based Medicine I wrote an article about the embrace by PETA (people for the ethical treatment of animals) of pseudoscience – in this case they are engaging in a fearmongering campaign linking dairy products to the risk of autism or increasing the severity of autism.

Yesterday I received an e-mail from PETA, essentially doubling down on their prior embrace of pseudoscience:

Dear Steven,

I want to follow up on your story last week about PETA’s campaign that points out how a dairy-free diet may help children with autism. PETA’s website and campaign serve to provide parents with potentially valuable information, albeit mostly anecdotal, from families’ findings—for example, just this week, the editor of Autism Eye magazine, Gillian Loughran, who has a 14-year-old son with autism, contacted us in support of our campaign and wrote a letter to the editor on our behalf (see below). Until such time as there is a large study into whether there is a dairy-autism link (and one we hope will not be funded by the dairy industry), it seems unwise to overlook a growing body of anecdotal information supporting that removing dairy and gluten from the diet of a child with autism may improve the child’s sleep, behavior, and concentration. We hope this letter will change your mind about PETA’s campaign—or, at least, that you will share this letter with your readers so that they can arrive at an informed opinion.

Thank you for your time.

Best regards,

Heather 

There are multiple problems with this position.

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Jun 02 2014

The Clinical Evidence for Homeopathy

Dana Ullman is a notorious apologist for homeopathy. He has a reputation, at least among skeptics, for cherry picking data and making dubious arguments – whatever it takes in order to defend his beloved homeopathy. He then tops it off by accusing skeptics of being closed-minded for not accepting his drivel.

An article of his recently popped up on the Skeptic subreddit (posted by rzeczpospolita) with the challenge, “Countless scientific studies showing that homeopathy works. Or are you “skeptics” too closed minded to accept this fact?”

The article is too long to deconstruct in one blog post, so I will focus on the key claim – that clinical evidence demonstrates that homeopathy works. His primary piece of evidence is this:

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May 30 2014

Measles Coming Back

There are some topics I just have to revisit from time to time. I consider this a public service announcement. So far this year there have been 288 confirmed cases of measles. This is the largest number of cases since endemic measles was declared eliminated from the US. The previous worse year was 2011, which saw 220 cases total. 

There is no question that this is tied to vaccine non-compliance. The anti-vaccine movement is scaring people with misinformation and pseudoscience into not vaccinating their children, and as a result we are seeing the return of vaccine-preventable diseases.

When a disease is endemic that means there is a self-sustaining infection – there is always someone infected somewhere and it keeps getting passed around. The MMR vaccine (especially after the second dose was added) resulted in herd immunity, which is a high enough immunity rate so that the infectious disease cannot be passed around indefinitely. High vaccination rates in the US resulted in eliminated measles as an endemic disease by 2000.

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May 22 2014

CIA Ends Vaccine Cover

The White House has announced that in August of 2013 CIA policy banned the use of vaccination programs as cover for CIA ops. Thus, hopefully, ends a blatantly unethical policy.

Back in 2011, the CIA suspected that they had located Osama Bin Laden in a compound in Abbottabad, Pakistan. They needed to confirm his presence, however. So they created a fake vaccine drive. They enlisted the help of a local physician and health official, Shakil Afridi, who set up a program to give free hepatitis B vaccines (all funded by the CIA). The goal of the vaccine program was to procure DNA from children in the compound to see if they were related to Bin Laden, thus confirming his presence.

The ploy worked, and as you probably know, Bin Laden’s compound was raided and he was summarily executed.

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