Oct 06 2014

Italy Smacks Down “Rogue” Stem Cell Clinic

Cases such as this highlight for me the need to have a clear understanding of the actual issues that underlie controversies. With regard to medicine, there is a clear need for a standard of care in order to protect the public from snake oil, charlatans and incompetence.

Promoters of therapies and health products that do not meet a reasonable standard are always distracting from the real issue by trying to make it about something else – freedom, conspiracies, East vs West, or philosophy. This unfortunately works, at least with some people.

However, if you ask people – do you think medical treatments should be supported by sound science, most will say yes. Do you think the government should protect the public from harmful or useless products with deceptive claims, most think this is already the case.

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Oct 03 2014

Are Health Apps Helpful?

There seems to be an app for everything, although we are just at the beginning of this new technology. It is a very recent phenomenon that many people in industrialized nations are walking around with a hand-held networked computer. This creates a new opportunity – to have constant access to applications that can help us run our lives. Even though there are already millions of apps, we really are just beginning to explore this opportunity.

One category of apps that seem to have a great deal of potential are health-related apps. There are apps to help people count calories, track their migraines, track their exercise, or even look up medical information or take a crack at diagnosing their own symptoms. There are apps to help you quit smoking or using alcohol, manage your medications, track your diabetes, or to provide some automatic therapy for mental illness.

The UK’s NHS maintains a list of approved health apps with hundreds of vetted apps you can browse.

In there are some useful ideas, and not-so-useful ideas. Trial and error will sort that out over time, and there are probably some killer health apps waiting to be developed.

How evidence-based are typical health apps, however? How would we even study that question?

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Oct 02 2014

Wind Turbine Syndrome

It looks like sustainable energy sources are going to be playing a larger role in our energy infrastructure in the future. Wind and solar are what first come to mind, but there is also hydroelectric, geothermal, and wave-generated electricity.

With the introduction of any new technology, especially on a large scale, there are bound to be some issues. Giant wind turbines are sprouting up, and this has caused some protest among people who don’t like the presence of the behemoths near their homes. Some claim that the noise from wind turbines is causing them ill health effects.

What are the real risks and benefit of wind turbines?

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Sep 30 2014

Dr. Oz, Autism, and GMOs

It is no longer news that Dr. Oz has long ago abandoned any pretense to scientific rigor and is simply another scaremongering hawker of snake oil and nonsense. Still, it’s hard not to marvel when he sinks to a new low.

On a recent show Oz’s target was genetically modified organisms (GMO). This is not new for Oz, he has hosted anti-GMO activists in the past, warning his audience about non-existent health risks.

This time around Oz and his guest are claiming that pesticides used with certain GMO varieties may cause autism. Why is it always autism? It’s likely at least partly due to the fact that awareness of autism has been increasing in the last 2 decades, creating the false impression that autism itself is increasing. This leads to numerous false correlations (most famously with vaccines) and the assumption of cause and effect (often to support a preexisting bias). As you can see from the graph, however, the rise in autism diagnoses tightly correlates with increased organic food sales – but I guess you have to cherry pick the correlation you want.

The narrative that Oz spun for his audience was this: GMO is tied to pesticide use. Those pesticides are hazardous to your health, and specifically might cause autism. Organic food is pesticide free, and going organic can actually cure autism.

Every link in that chain of argument is misleading or patently wrong.

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Sep 29 2014

How Our Brains Respond to Ambiguous Images

A new study looks at how our brains respond to images of celebrities made ambiguous by morphing two images into one, such as the combination of Halle Berry and Angelina Jolie shown here. The question is – will our brains fire in a way that represents the details of the picture, or will they fire based upon how we perceive the picture?

The researchers were able to study subjects who had small electrodes placed on the surface of their brains for clinical purposes. Such electrodes are capable of detecting the firing of a single brain neuron. They showed the subjects pictures of two celebrities to see how their brains responded. Typically a single neuron, which encodes the memory of that particular celebrity, would fire. They then showed them a morphed picture and asked them to identify the celebrity.

When subjects recognized Halle Berry, for example, the single neuron that previously fired when viewing Halle Berry also fired.

This is an interesting, but not unexpected, result. How does this fit into our understanding of brain function?

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Sep 26 2014

FDA Takes On Essential Snake Oils

The Food and Drug Administration (FDA) is tasked with ensuring quality and transparency in the foods and drugs that are sold to consumers. This is a daunting task, and by all accounts the FDA is commonly understaffed, without the resources to thoroughly do its job. Further, politics often hamstrings the agency, so they don’t have the actual authority to do their job.

The most egregious example is the Dietary Supplement Health and Education Act of 1994 (DSHEA). This law (courtesy of Hatch and Harkin) effectively removed “supplements” out of the control of the FDA, and broadly defined supplements to include herbal drugs and other products that are not actually dietary supplements.

Essentially DSHEA created two categories of consumable health products. Drugs, by definition, are any products for which specific disease claims are being made. If you say your pill or ointment treats diabetes, then it’s a drug, because diabetes is a disease. A supplement, by definition, makes no claims to cure or treat a disease, but is allowed to make “structure function” claims. This is a giant loop hole manufactured by DSHEA and wrapped as a present for the supplement industry, at the expense of consumers.

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Sep 25 2014

Newtown and FBI Crime Statistics

On December 14, 2012, a disturbed shooter killed 20 children and 6 adult staff at the Sandy Hook Elementary School. This was a horrific event, and the community is still recovering.

Almost immediately after the shooting, and continuing to this day, conspiracy theorists have been shoe-horning this tragic event into their preferred narrative, calling the event a “false flag” operation. In other words, they believe that no children were killed on that day. The entire event was staged by the powers that be as a pretext to take away the guns of law-abiding citizens.

The claim is absurd on its face, but does provide an interesting window into how people can come to believe something that seems so “bat shit crazy.” It provides a lesson into the iron grip that a compelling narrative can have on someone’s mind.

The preferred narrative of the conspiracy theorist is that you cannot believe anything anyone in authority says. The government lies and only seeks to oppress us, so if the government says something it cannot be true. Anyone who believes the government is hopelessly naive.

So if “corporate media” is saying children were killed at Sandy Hook it must not be true, no matter how implausible the alternative might be.

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Sep 23 2014

Flavors of Nonsense

I, like most people, like to categorize things. It helps me keep my mental space organized and tidy. A good system of categorization is also like a framework on which I can hang specific facts and details. Categories are most useful when they reflect underlying reality, rather than superficial or arbitrary features. Categories are therefore often at the nexus of facts and theory in science – they can organize the facts in a way that reflects the underlying theory. 

You have to be cautious, however. Reality often does not cleave in clean straight lines. There are likely to be exceptions to any rules one devises for defining specific categories. Groups tend to be fuzzy around the edges. While categories can be a useful tool for organizing ideas, they can also become a mental prison or straightjacket.

Is Pluto a planet? It depends on how you define planet, and why you would define planet in any particular way. Is there a difference between planets, dwarf planets, and planetoids? Or do these objects exist along a spectrum and scientists are simply drawing arbitrary lines for convenience? Is schizophrenia one disease or a group of diseases, how do we categorize the subtypes, and do they reflect real underlying differences in cause? Are such labels helping or hindering research?

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Sep 22 2014

Vandana Shiva and GMOs

A recent New Yorker article by Michael Specter does an excellent job of putting the activism of anti-GMO campaigner, Vandana Shiva, into perspective. Shiva has since written a very critical response to Specter, and The New Yorker has responded to Shiva. The exchange is very enlightening.

Shiva is a dedicated anti-GMO activist, perhaps the most widely known and successful in the world. Specter paints a picture of Shiva as more than an ideologue – a “demagogue” who has created a dramatic narrative that is meant to frighten the public about GMOs, but has little to do with reality. For Shiva, her anti-GMO stance is part of a broader economic and social ideology. In her vision of the world, local farmers would feed the world with organic farming, without fertilizer or corporate involvement. The actual science about GMOs seems to be irrelevant to her narrative.

Specter illustrates several example. There are definitely religious undertones to her activism. For example, Specter quotes her from a speech earlier this year:

“G.M.O. stands for ‘God, Move Over,’ we are the creators now,”

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Sep 19 2014

How To Be a Science Denier

This Week Louisiana Governor Bobby Jindal gave an excellent lesson on how to be a science denier. Unfortunately, this was not a faux demonstration, he was sincere.

If you recall, in 2012, Jindal advised Republicans to stop being “the stupid party.” This was a provocative statement. I wondered at the time if this signaled a shift in the party away from having anti-science on their platform. Had party insiders finally realized they can’t hang their political future on denying undeniable science, that they need to embrace reality and stop fighting against it?

Alas, it seems that a more cynical interpretation is closer to the truth – that Jindal was simply worried about damage to the Republican brand caused by Republicans saying “offensive, bizarre” comments, but not by the substance of their positions on scientific issues.

At a recent breakfast hosted by the Christian Science Monitor, Jindal was introduced as a Brown graduate at the age of 20 with a biology major, then a Rhodes Scholar at Oxford, and having a 2 year stint as the president of the University of Louisiana, along with many other accomplishments. So he is a scholar and, to some extent, an academic, with advanced study in biology specifically.

During the breakfast, which included journalists, Jindal was asked about global warming. In response to this issue, Jindal performed a very deft dance. He said, “Let the scientists decide,” referring to whether or not global warming is happening. This, of course, is a clever denialist tactic. The hidden premise here is that the scientists have not already spoken with a unified and loud voice. They have decided – it is clear that human activity is increasing greenhouse gases in the atmosphere and warming the climate.

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