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	<title>Comments on: How Much Modern Medicine is Evidence-Based</title>
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	<description>Your Daily Fix of Neuroscience, Skepticism, and Critical Thinking</description>
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		<title>By: healthman</title>
		<link>http://theness.com/neurologicablog/index.php/how-much-modern-medicine-is-evidence-based/comment-page-1/#comment-13621</link>
		<dc:creator>healthman</dc:creator>
		<pubDate>Wed, 12 Aug 2009 00:35:24 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=51#comment-13621</guid>
		<description>Actually, there are more current references to the 50% and 15% numbers that make them somewhat less &quot;mythical.&quot;

&quot;More than half of all medical treatments, and perhaps as many as 85 percent, have never been validated by clinical trials.&quot; Michael L. Millenson, AB: Demanding Medical Evidence: Doctors and Accountability in the Information Age, The Robert Wood Johnson Foundation, Issue 2, September 1998.

&quot;Only 10-20% of all procedures currently used in medical practice have been shown to be efficacious by controlled trial.&quot; Office of Technology Assessment, US Congress. Assessing the Efficacy and Safety of Medical Technologies. Washington DC : Office of Technology Assessment, US Congress; 1978.</description>
		<content:encoded><![CDATA[<p>Actually, there are more current references to the 50% and 15% numbers that make them somewhat less &#8220;mythical.&#8221;</p>
<p>&#8220;More than half of all medical treatments, and perhaps as many as 85 percent, have never been validated by clinical trials.&#8221; Michael L. Millenson, AB: Demanding Medical Evidence: Doctors and Accountability in the Information Age, The Robert Wood Johnson Foundation, Issue 2, September 1998.</p>
<p>&#8220;Only 10-20% of all procedures currently used in medical practice have been shown to be efficacious by controlled trial.&#8221; Office of Technology Assessment, US Congress. Assessing the Efficacy and Safety of Medical Technologies. Washington DC : Office of Technology Assessment, US Congress; 1978.</p>
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		<title>By: Science-Based Medicine &#187; Vertebroplasty for compression fractures due to osteoporosis: Placebo medicine</title>
		<link>http://theness.com/neurologicablog/index.php/how-much-modern-medicine-is-evidence-based/comment-page-1/#comment-13586</link>
		<dc:creator>Science-Based Medicine &#187; Vertebroplasty for compression fractures due to osteoporosis: Placebo medicine</dc:creator>
		<pubDate>Mon, 10 Aug 2009 17:33:48 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=51#comment-13586</guid>
		<description>[...] even though the proportion of medical therapies not based on science is far lower than CAM advocates would like you to believe, there are still more treatments in &#8220;conventional&#8221; medicine that are insufficiently [...]</description>
		<content:encoded><![CDATA[<p>[...] even though the proportion of medical therapies not based on science is far lower than CAM advocates would like you to believe, there are still more treatments in &#8220;conventional&#8221; medicine that are insufficiently [...]</p>
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		<title>By: A Few Common Pro-CAM Arguments and Soem Possibel Responses &#171; The SkeptVet Blog</title>
		<link>http://theness.com/neurologicablog/index.php/how-much-modern-medicine-is-evidence-based/comment-page-1/#comment-13250</link>
		<dc:creator>A Few Common Pro-CAM Arguments and Soem Possibel Responses &#171; The SkeptVet Blog</dc:creator>
		<pubDate>Wed, 22 Jul 2009 22:15:07 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=51#comment-13250</guid>
		<description>[...] There are several versions of the &#8220;you too&#8221; argument. One is that mainstream medicine is itself not evidence or science based and so CAM has an equal claim to legitimacy and efficacy. The specific citation that “only 15% of allopathic medical treatments were based on scientific studies” has been well-debunked. [...]</description>
		<content:encoded><![CDATA[<p>[...] There are several versions of the &#8220;you too&#8221; argument. One is that mainstream medicine is itself not evidence or science based and so CAM has an equal claim to legitimacy and efficacy. The specific citation that “only 15% of allopathic medical treatments were based on scientific studies” has been well-debunked. [...]</p>
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		<title>By: NeuroLogica Blog &#187; Responding to Dana Ullman</title>
		<link>http://theness.com/neurologicablog/index.php/how-much-modern-medicine-is-evidence-based/comment-page-1/#comment-1996</link>
		<dc:creator>NeuroLogica Blog &#187; Responding to Dana Ullman</dc:creator>
		<pubDate>Mon, 24 Mar 2008 17:06:49 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=51#comment-1996</guid>
		<description>[...] It is difficult to estimate the degree to which mainstream medicine is science-based, because this is not a black-and-white issue, but credible estimates are that 78% of what physicians do has a solid grounding in science and evidence (which is much more than the bogus figure of 15% often cited by CAM proponents). I discuss this question in more detail here. [...]</description>
		<content:encoded><![CDATA[<p>[...] It is difficult to estimate the degree to which mainstream medicine is science-based, because this is not a black-and-white issue, but credible estimates are that 78% of what physicians do has a solid grounding in science and evidence (which is much more than the bogus figure of 15% often cited by CAM proponents). I discuss this question in more detail here. [...]</p>
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		<title>By: jasonb</title>
		<link>http://theness.com/neurologicablog/index.php/how-much-modern-medicine-is-evidence-based/comment-page-1/#comment-595</link>
		<dc:creator>jasonb</dc:creator>
		<pubDate>Fri, 30 Nov 2007 09:01:48 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=51#comment-595</guid>
		<description>Not so fast.  I was actually able to share emails with Ms. Brownlee who had this to offer,

&quot;The 50 percent figure comes from none other than the Institute of Medicine. Not exactly a bunch of pro-alternative medicine nutjobs.&quot;  

And she goes on.

&quot;Here&#039;s a short list right off the top of my head of widespread medical practices that have only recently been shown to be ineffective or harmful for at least some patients on whom they were commonly used: cadiac stents vs medical management; neurontin for biopolar disorder; vena cava filter in patients on low molecular-weight heparin; implantable defibrilators; lung
 reduction surgery for emphysema; pulmonary artery catheters, carotid endarterectomy for most patients. There are many many more.&quot;
 
&quot;Here&#039;s an off the top of the head list of current, common medical practices that have poor, contradictory, or no evidence; spinal fusion for low back pain; minimally invasive hip replacement surgery; orthognathic surgery for TMJ; PET scanning for putative Alzheimer&#039;s; TpA for stroke; statins for primary prevention; PSA testing for prostate cancer; CT scan screening for lung cancer; stents for the prevention of stroke. I could go on and on.&quot; 
 
&quot;There is widespread antipathy towards evidence within the medical community, I think at least in part because it is very hard for physicians to admit they are practicing medicine on the basis of  hunches, tradition, and all the other non-science-based reasons that doctors do what
 they do. The problem is, most doctors are not trained to tell the difference between valid evidence and garbage, much less valid evidence and somewhat less reliable evidence -- the difference, for instance, between a randomized controlled clinical trial and an observational trial. Many think observation is just as good.&quot; 

Out of all the sciences, it is the medical profession that sports the highest percentage of belief in supernaturalism (i.e., god).  It&#039;s no wonder there&#039;s so much bullshit being passed off as &quot;good, solid medical practice.&quot;  And for you to not go after these things as passionately as you do CAM, is frankly a big disappointment.  I love when you call bullshit on the CAMers.  Now, step up and learn to call BS even when it hits close to home.</description>
		<content:encoded><![CDATA[<p>Not so fast.  I was actually able to share emails with Ms. Brownlee who had this to offer,</p>
<p>&#8220;The 50 percent figure comes from none other than the Institute of Medicine. Not exactly a bunch of pro-alternative medicine nutjobs.&#8221;  </p>
<p>And she goes on.</p>
<p>&#8220;Here&#8217;s a short list right off the top of my head of widespread medical practices that have only recently been shown to be ineffective or harmful for at least some patients on whom they were commonly used: cadiac stents vs medical management; neurontin for biopolar disorder; vena cava filter in patients on low molecular-weight heparin; implantable defibrilators; lung<br />
 reduction surgery for emphysema; pulmonary artery catheters, carotid endarterectomy for most patients. There are many many more.&#8221;</p>
<p>&#8220;Here&#8217;s an off the top of the head list of current, common medical practices that have poor, contradictory, or no evidence; spinal fusion for low back pain; minimally invasive hip replacement surgery; orthognathic surgery for TMJ; PET scanning for putative Alzheimer&#8217;s; TpA for stroke; statins for primary prevention; PSA testing for prostate cancer; CT scan screening for lung cancer; stents for the prevention of stroke. I could go on and on.&#8221; </p>
<p>&#8220;There is widespread antipathy towards evidence within the medical community, I think at least in part because it is very hard for physicians to admit they are practicing medicine on the basis of  hunches, tradition, and all the other non-science-based reasons that doctors do what<br />
 they do. The problem is, most doctors are not trained to tell the difference between valid evidence and garbage, much less valid evidence and somewhat less reliable evidence &#8212; the difference, for instance, between a randomized controlled clinical trial and an observational trial. Many think observation is just as good.&#8221; </p>
<p>Out of all the sciences, it is the medical profession that sports the highest percentage of belief in supernaturalism (i.e., god).  It&#8217;s no wonder there&#8217;s so much bullshit being passed off as &#8220;good, solid medical practice.&#8221;  And for you to not go after these things as passionately as you do CAM, is frankly a big disappointment.  I love when you call bullshit on the CAMers.  Now, step up and learn to call BS even when it hits close to home.</p>
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		<title>By: Respectful Insolence</title>
		<link>http://theness.com/neurologicablog/index.php/how-much-modern-medicine-is-evidence-based/comment-page-1/#comment-538</link>
		<dc:creator>Respectful Insolence</dc:creator>
		<pubDate>Thu, 22 Nov 2007 16:50:24 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=51#comment-538</guid>
		<description>&lt;strong&gt;How much of modern medicine is &quot;evidence-based&quot;? (briefly revisited)...&lt;/strong&gt;

I once blogged about an article attempting to address the very question in the title of this post, and I&#039;ve also discussed in depth how messy the process of evidence-based medicine can be and why that provides an opening for......</description>
		<content:encoded><![CDATA[<p><strong>How much of modern medicine is &#8220;evidence-based&#8221;? (briefly revisited)&#8230;</strong></p>
<p>I once blogged about an article attempting to address the very question in the title of this post, and I&#8217;ve also discussed in depth how messy the process of evidence-based medicine can be and why that provides an opening for&#8230;&#8230;</p>
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		<title>By: How much of modern medicine is &#34;evidence-based&#34;? (briefly revisited) [Respectful Insolence] &#124; NewAge.org</title>
		<link>http://theness.com/neurologicablog/index.php/how-much-modern-medicine-is-evidence-based/comment-page-1/#comment-533</link>
		<dc:creator>How much of modern medicine is &#34;evidence-based&#34;? (briefly revisited) [Respectful Insolence] &#124; NewAge.org</dc:creator>
		<pubDate>Thu, 22 Nov 2007 01:12:32 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=51#comment-533</guid>
		<description>[...] I know. I&#8217;m grateful to Steve Novella for telling me. It turns out that the 15% figure dates back nearly a half-century ago, all the way [...]</description>
		<content:encoded><![CDATA[<p>[...] I know. I&#8217;m grateful to Steve Novella for telling me. It turns out that the 15% figure dates back nearly a half-century ago, all the way [...]</p>
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		<title>By: How much of modern medicine is &#8220;evidence-based&#8221;? (briefly revisited) [Respectful Insolence] &#183; New York Articles</title>
		<link>http://theness.com/neurologicablog/index.php/how-much-modern-medicine-is-evidence-based/comment-page-1/#comment-526</link>
		<dc:creator>How much of modern medicine is &#8220;evidence-based&#8221;? (briefly revisited) [Respectful Insolence] &#183; New York Articles</dc:creator>
		<pubDate>Wed, 21 Nov 2007 19:33:53 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=51#comment-526</guid>
		<description>[...] I know. I&#8217;m grateful to Steve Novella for telling me. It turns out that the 15% figure dates back nearly a half-century ago, all the way [...]</description>
		<content:encoded><![CDATA[<p>[...] I know. I&#8217;m grateful to Steve Novella for telling me. It turns out that the 15% figure dates back nearly a half-century ago, all the way [...]</p>
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		<title>By: Amy Alkon</title>
		<link>http://theness.com/neurologicablog/index.php/how-much-modern-medicine-is-evidence-based/comment-page-1/#comment-522</link>
		<dc:creator>Amy Alkon</dc:creator>
		<pubDate>Wed, 21 Nov 2007 09:37:25 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=51#comment-522</guid>
		<description>I am no fan of &quot;alternative medicine&quot; (I like the Angell/Kassirer quote: &quot;...There is only medicine that has been adequately tested and medicine that has not, medicine that works and medicine that may or may not work.&quot;)

That said, there&#039;s a great deal of fudging of statistics in what we consider evidence-based medicine...so while I&#039;m absolutely for evidence-based medicine (as opposed to the recommendations of gray-skinned health food store employees)...exactly how evidence-based is some (or even much) of this evidence-based medicine?

The problem is, it probably takes some of the finer stats hounds/epidemiologists to properly deconstruct the math behind the studies, leaving the rest of us to simply hope that what we consider &quot;evidence-based&quot; medicine actually is.

Again, no fan of woo here...but I think there&#039;s a tendency in opposiing woo to deify the other side. Skepticism all around is called for: Science, as opposed to &quot;science.&quot;</description>
		<content:encoded><![CDATA[<p>I am no fan of &#8220;alternative medicine&#8221; (I like the Angell/Kassirer quote: &#8220;&#8230;There is only medicine that has been adequately tested and medicine that has not, medicine that works and medicine that may or may not work.&#8221;)</p>
<p>That said, there&#8217;s a great deal of fudging of statistics in what we consider evidence-based medicine&#8230;so while I&#8217;m absolutely for evidence-based medicine (as opposed to the recommendations of gray-skinned health food store employees)&#8230;exactly how evidence-based is some (or even much) of this evidence-based medicine?</p>
<p>The problem is, it probably takes some of the finer stats hounds/epidemiologists to properly deconstruct the math behind the studies, leaving the rest of us to simply hope that what we consider &#8220;evidence-based&#8221; medicine actually is.</p>
<p>Again, no fan of woo here&#8230;but I think there&#8217;s a tendency in opposiing woo to deify the other side. Skepticism all around is called for: Science, as opposed to &#8220;science.&#8221;</p>
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		<title>By: nfpendleton</title>
		<link>http://theness.com/neurologicablog/index.php/how-much-modern-medicine-is-evidence-based/comment-page-1/#comment-521</link>
		<dc:creator>nfpendleton</dc:creator>
		<pubDate>Wed, 21 Nov 2007 08:55:20 +0000</pubDate>
		<guid isPermaLink="false">http://www.theness.com/neurologicablog/?p=51#comment-521</guid>
		<description>I know this is a day late and a dollar short, and maybe not exactly on topic, but this blog post reminds me of a comment James Herriot made in his first book, All Creatures Great And Small.  To paraphrase, he stated that much of the &quot;medicines&quot; they used in those days (late 30&#039;s) were just useless cocktails no more potent than home remedies.  In the days before antibiotics, vet med was lax on real science and reliant on what we now call CAM.  And, if I recall the success rate of these treatments, they were just as effective then as now.  He lost at least as many patients as he saved.

Flash forward to today and all the progress made in the interum...

These assertions you highlight are just wreckless and irresponsible.  There&#039;s just too little old fashioned shame where these truthers are concerned.  Corny perhaps; but true most likely.</description>
		<content:encoded><![CDATA[<p>I know this is a day late and a dollar short, and maybe not exactly on topic, but this blog post reminds me of a comment James Herriot made in his first book, All Creatures Great And Small.  To paraphrase, he stated that much of the &#8220;medicines&#8221; they used in those days (late 30&#8242;s) were just useless cocktails no more potent than home remedies.  In the days before antibiotics, vet med was lax on real science and reliant on what we now call CAM.  And, if I recall the success rate of these treatments, they were just as effective then as now.  He lost at least as many patients as he saved.</p>
<p>Flash forward to today and all the progress made in the interum&#8230;</p>
<p>These assertions you highlight are just wreckless and irresponsible.  There&#8217;s just too little old fashioned shame where these truthers are concerned.  Corny perhaps; but true most likely.</p>
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