Archive for the 'Science and Medicine' Category

Aug 12 2014

Tocco’s Anti-vaccine Narrative

Part of the scientific approach to knowledge is to integrate information at various levels. It’s important to get the tiny facts correct, but you also have to put those facts into progressively broader and deeper frameworks. Theories are informed by facts which in turn make sense only in the context of the theory.

I try to take this approach with topics on this blog, by not only spending time addressing specific facts but also trying to see the big picture. For example, Mary Tocco, who is an anti-vaccine activist, was recently given space for a guest column on Michigan Live. I will go through and deconstruct her specific claims, but it’s also helpful to view her article in the broader social context.

Tocco is part of Michigan Opposing Mandatory Vaccination, or MOM (how can you not love “mom”). In her article she writes:

“The authors labeled Michigan Opposing Mandatory Vaccines an anti-vaccine group. Our organization is about protecting parental right to choose whether or not to use vaccines as a method of health care for themselves and their children.”

From this one paragraph we can see many of the threads currently weaving through culture. The big picture is that there is an ideological struggle going on between those who take a science-based worldview and believe that rational regulations should be based on the best science available, and those who wish to promote some other agenda that is not science-based.

Continue Reading »

Share

8 responses so far

Aug 04 2014

Ebola Pseudoscience

It is natural for there to be a certain amount of fear and uncertainty surrounding the reported outbreak of a deadly virus. The recent ebola outbreak is the worst in history, with over 800 deaths reported out of over 1,400 infections (case fatality rate so far of 57%).

Crises like these tend to bring out the best and the worst in people. Health care workers are literally risking their lives to contain this outbreak. Meanwhile, charlatans are coming out of the woodwork to exploit the crisis to spread their nonsense.

Ebola was first discovered in 1976. The virus exists in central and western Africa, and outbreaks are usually small, involving isolated villages. The virus can exist in fruit bats, which is the usual reservoir that spreads to humans. Other animals can be the vector, however, including chimpanzees, gorillas, monkeys, forest antelope and porcupines. Once a human infection occurs, however, the virus can spread from person to person.

Continue Reading »

Share

25 responses so far

Jul 25 2014

Mike Adams is a Dangerous Loon

Where do I even begin? Mike Adams, the self-proclaimed “healthranger” who runs the crank alt-med site naturalnews, has sunk to a new low, even though he was already scraping bottom.

Adams combines the worst CAM propaganda with a blend of conspiracy theories from across the spectrum, while selling supplements and other nonsense. He portrays himself as someone who is engaged in a righteous battle against the forces of evil – so hardly someone who is engaged in rational discourse.

In a recent rant, however, he has become a parody even of himself. This time he is raving about Monsanto and GMOs, writing:

Monsanto is widely recognize (sic) as the most hated and most evil corporation on the planet. Even so, several internet-based media websites are now marching to Monsanto’s orders, promoting GMOs and pursuing defamatory character assassination tactics against anyone who opposes GMOs, hoping to silence their important voices.

Continue Reading »

Share

271 responses so far

Jul 23 2014

Another Lawsuit To Suppress Legitimate Criticism – This Time SBM

I suppose it was inevitable. In fact, I’m a bit surprised it took this long. SGU Productions, the Society for Science-based medicine, and I are being sued for an article that I wrote in May of 2013 on Science-Based Medicine. My SBM piece, which was inspired by an article in the LA Times, gave this summary:

“The story revolves around Dr. Edward Tobinick and his practice of perispinal etanercept (Enbrel) for a long and apparently growing list of conditions. Enbrel is an FDA-approved drug for the treatment of severe rheumatoid arthritis. It works by inhibiting tumor necrosis factor (TNF), which is a group of cytokines that are part of the immune system and cause cell death. Enbrel, therefore, can be a powerful anti-inflammatory drug. Tobinick is using Enbrel for many off-label indications, one of which is Alzheimer’s disease (the focus of the LA Times story).”

The claims and practice of Dr. Tobinick have many of the red flags of a dubious medical practice, of the sort that we discuss regularly on SBM. It seems that Dr. Tobinick does not appreciate public criticism of his claims and practice, and he wants me to remove the post from SBM. In my opinion he is using legal thuggery in an attempt to intimidate me and silence my free speech because he finds its content inconvenient.

Of course, we have no intention of removing the post as we feel it is critical to the public’s interest. This is what we do at SBM – provide an objective analysis of questionable or controversial medical claims so that consumers can make more informed decisions, and to advance the state of science in medicine.
We also feel it is critical not to cave to this type of intimidation. If we do, we might as well close up shop (which I suspect the Tobinicks of the world would find agreeable). Defending against even a frivolous lawsuit can be quite expensive, but we feel it is necessary for us to fight as hard as we can to defend our rights and the work that we do here at SBM.

Continue Reading »

Share

30 responses so far

Jul 18 2014

New Organic Farming Meta-analysis – What Does it Really Show?

The Guardian’s headline reads: Clear differences between organic and non-organic food, study finds. While this article was better than most in including some caveats, it was clearly favorable to the conclusions in the study, and failed, in my opinion, to properly put the new study into an informative context.

How does this new study add to the literature looking at the safety and health effect of organic produce vs conventional produce?

First, the study is a meta-analysis of 343 prior studies looking at nutrient content, pesticide, and heavy metal contamination of produce. It is not a collection of any new data. A meta-analysis is very tricky to conduct well – it does not improve the quality of the data going into the analysis, only the statistical power. Further it introduces another layer of potential bias (another researcher degree of freedom) in which studies are chosen for the analysis.

This study used very open criteria, and therefore included more lower-quality studies (likely to be false positive or show the bias of the researchers) than other meta-analyses.

Continue Reading »

Share

30 responses so far

Jul 15 2014

BBC Fail on Acupuncture Documentary

Alternative Medicine’s best friend, and in my opinion largely responsible for what popularity it has, is a gullible media. I had thought we were turning a corner, and the press were over the gushing maximally clueless approach to CAM, and were starting to at least ask some probing questions (like, you know, does it actually work), but a 2006 BBC documentary inspires a more pessimistic view.

The documentary is part of a BBC series hosted by Kathy Sykes: Alternative Medicine, The Evidence. This episode is on acupuncture. The episode is from 2006, but was just posted on YouTube as a “2014 documentary.” Unfortunately, old news frequently has a second life on social media.

First, let me point out that Sykes is a scientist (a fact she quickly points out). She is a physicist, which means that she has the credibility of being able to say she is a scientist but has absolutely no medical training. It’s the worst case scenario – she brings the credibility of being a scientist, and probably thinks that her background prepares her to make her own judgments about the evidence, and yet clearly should have relied more on real experts.

Continue Reading »

Share

24 responses so far

Jul 03 2014

Vaccine Safety Systematic Review

A new systematic review of adverse events from vaccines used in the US was recently published in the journal Pediatrics: Safety of Vaccines Used for Routine Immunization of US Children: A Systematic Review. (Full text pdf) This systematic review is actually an update and expansion to the 2011 Institute of Medicine (IOM) report on vaccine side effects.

The review looked at the best evidence available, active surveillance studies with controls, identifying 67 relevant studies. Overall they found that vaccines were very safe. There were a few associations with serious adverse events, but these were all very rare. From their conclusions:

Our findings may allay some patient, caregiver, and health care provider concerns. Strength of evidence is high that MMR vaccine is not associated with the onset of autism in children; this conclusion supports findings of all previous reviews on the topic. There is also high-strength evidence that MMR, DTaP, Td, Hib, and hepatitis B vaccines are not associated with childhood leukemia.

Evidence was found for an association of several serious AEs with vaccines; however, these events were extremely rare: absolute risk is low. For example, strength of evidence is moderate for association of vaccines against rotavirus with intussusception. Although 1 large US epidemiologic study found no association, a recent analysis of the US PRISM program found both RotaTeq and Rotarix associated with intussusception in the short term. Estimated rates were 1.1 to 1.5 cases per 100 000 doses of RotaTeq and 5.1 cases per 100 000 doses of Rotarix.

So a few vaccines are associated with rare AEs. Given the rhetoric of the anti-vaccine movement, there are a few points worth emphasizing here.

Continue Reading »

Share

13 responses so far

Jun 26 2014

Pesticides and Autism

A study has been making the rounds on social media claiming an association between prenatal exposure to pesticides and the risk of autism and developmental delay. This means that I am getting asked by many people what the study actually shows. Spoiler alert – not much. But let’s break it down.

Autism spectrum disorder (ASD) is a neurological disorder involving brain development resulting in decreased communications among neurons in the brain and characterized by reduced social ability. Our current scientific understanding is that ASD is largely a genetic disorder. While environmental factors cannot be ruled out, it seems that genes are the primary factor. It’s reasonable to search for environmental risk factors, but so far none have been clearly established.

Those who feel there likely is an environmental factor also tend to believe that there is an autism epidemic – that the incidence of autism is increasing in a way that is not easily explained by genetics, and therefore suggests and environmental factor. While it is uncontroversial that the number of ASD diagnoses has been increasing over the last two decades, this does not necessarily mean that the true incidence of ASD has been increasing.

The evidence actually shows that diagnostic substitution, broadening of the definition of ASD, and increased surveillance account for much of the increased recorded incidence. It’s possible that changes in diagnostic behavior entirely accounts for the apparent increase. It’s also possible that a subset is due to a true increase, but that has not been clearly established.

Continue Reading »

Share

16 responses so far

Jun 06 2014

PETA Responds

Last week on Science-Based Medicine I wrote an article about the embrace by PETA (people for the ethical treatment of animals) of pseudoscience – in this case they are engaging in a fearmongering campaign linking dairy products to the risk of autism or increasing the severity of autism.

Yesterday I received an e-mail from PETA, essentially doubling down on their prior embrace of pseudoscience:

Dear Steven,

I want to follow up on your story last week about PETA’s campaign that points out how a dairy-free diet may help children with autism. PETA’s website and campaign serve to provide parents with potentially valuable information, albeit mostly anecdotal, from families’ findings—for example, just this week, the editor of Autism Eye magazine, Gillian Loughran, who has a 14-year-old son with autism, contacted us in support of our campaign and wrote a letter to the editor on our behalf (see below). Until such time as there is a large study into whether there is a dairy-autism link (and one we hope will not be funded by the dairy industry), it seems unwise to overlook a growing body of anecdotal information supporting that removing dairy and gluten from the diet of a child with autism may improve the child’s sleep, behavior, and concentration. We hope this letter will change your mind about PETA’s campaign—or, at least, that you will share this letter with your readers so that they can arrive at an informed opinion.

Thank you for your time.

Best regards,

Heather 

There are multiple problems with this position.

Continue Reading »

Share

96 responses so far

Jun 02 2014

The Clinical Evidence for Homeopathy

Dana Ullman is a notorious apologist for homeopathy. He has a reputation, at least among skeptics, for cherry picking data and making dubious arguments – whatever it takes in order to defend his beloved homeopathy. He then tops it off by accusing skeptics of being closed-minded for not accepting his drivel.

An article of his recently popped up on the Skeptic subreddit (posted by rzeczpospolita) with the challenge, “Countless scientific studies showing that homeopathy works. Or are you “skeptics” too closed minded to accept this fact?”

The article is too long to deconstruct in one blog post, so I will focus on the key claim – that clinical evidence demonstrates that homeopathy works. His primary piece of evidence is this:

Continue Reading »

Share

114 responses so far

« Prev - Next »